1 – Human Fallopian Tube Organoids
Researchers who have worked on this axis:
- Prof. E. Huyghe
- Dr. N. Gatimel
- Dr. G. Perez
To contact a reference person on this research axis, please call Françoise Paris at 06 15 10 63 71.
a) Issue
Despite advances in ART, live birth rates per IVF attempt remain relatively low. These results are largely determined by the competence of the embryos obtained during IVF. The competence of the embryos obtained is determined by that of the gametes from which they originate, as well as by the technical conditions implemented for the stages of fertilization, embryonic development, or cryopreservation. The competence of spermatozoa is among other things highly dependent on their tubal journey, although the mechanisms remain poorly understood.
b) Human Fallopian Tube Organoids Project
These tubal organoids should improve understanding of tubal physiology as well as the environment favorable to gamete survival and preimplantation embryo development. This knowledge may also contribute to improving Assisted Reproductive Technology techniques.
